Posts belonging to Category 'Travaux scientifiques'

Assessment of typical SpA lesions on MRI of the spine: do local readers and central readers agree in the DESIR-cohort at baseline

Un nouvel article scientifique intitulé «Assessment of typical SpA lesions on MRI of the spine: do local readers and central readers agree in the DESIR-cohort at baseline » a été publié dans le journal Clin Rheumatol.
de Hooge M, Pialat JB, Reijnierse M, van der Heijde D, Claudepierre P, Saraux A, Dougados M, Feydy [...]

Reliability of mSASSS scoring in everyday practice in DESIR-cohort study centres: cross-sectional study of agreement with trained readers.

Un nouvel article scientifique intitulé Reliability of mSASSS scoring in everyday practice in DESIR-cohort study centres: cross-sectional study of agreement with trained readers..» a été publié dans le journal Ann Rheum Dis.
Claudepierre P, de Hooge M, Feydy A, Reijnierse M, Saraux A, Dougados M, van der Heijde D
Ann Rheum Dis. 2016 Dec;75(12):2213-2214. doi: [...]

What is the reliability of non-trained investigators in recognising structural MRI lesions of sacroiliac joints in patients with recent inflammatory back pain? Results of the DESIR cohort.

Un nouvel article scientifique intitulé «What is the reliability of non-trained investigators in recognising structural MRI lesions of sacroiliac joints in patients with recent inflammatory back pain? Results of the DESIR cohort.» a été publié dans le journal RMD Open.
Jacquemin C, Rubio Vargas R, van den Berg R, Thévenin F, Lenczner G, Reijnierse [...]

Disease activity trajectories in early axial spondyloarthritis: results from the DESIR cohort.

Un nouvel article scientifique intitulé «Remission is related to CRP and smoking in early axial spondyloarthritis. The DESIR cohort.» a été publié dans le journal Ann Rheum Dis.
Molto A, Tezenas du Montcel S, Wendling D, Dougados M, Vanier A, Gossec L
Ann Rheum Dis. 2016 Nov 25. pii: annrheumdis-2016-209785.
Abstract
BACKGROUND:
Disease activity may change over time in axial [...]

Remission is related to CRP and smoking in early axial spondyloarthritis. The DESIR cohort.

Un nouvel article scientifique intitulé «Remission is related to CRP and smoking in early axial spondyloarthritis. The DESIR cohort.» a été publié dans le journal Joint Bone Spine.
Wendling D, Guillot X, Gossec L, Prati C, Saraux A, Dougados M
Joint Bone Spine. 2016 Jul 20. doi: 10.1016/j.jbspin.2016.06.004
Abstract

INTRODUCTION:
No evaluation of factors associated with remission has been [...]

Can we use structural lesions seen on MRI of the sacroiliac joints reliably for the classification of patients according to the ASAS axial spondyloarthritis criteria? Data from the DESIR cohort

Abstract
OBJECTIVES:

Investigating the utility of adding structural lesions seen on MRI of the sacroiliac joints to the imaging criterion of the Assessment of SpondyloArthritis (ASAS) axial SpondyloArthritis (axSpA) criteria and the utility of replacement of radiographic sacroiliitis by structural lesions on MRI.
METHODS:

Two well-calibrated readers scored MRI STIR (inflammation, MRI-SI), MRI T1-w images (structural lesions, MRI-SI-s) and radiographs of the sacroiliac joints (X-SI) of patients in the DEvenir des Spondyloarthrites Indifférenciées Récentes cohort (inflammatory back pain: ≥3 months, <3 years, age <50). A third reader adjudicated MRI-SI and X-SI discrepancies. Previously proposed cut-offs for a positive MRI-SI-s were used (based on <5% prevalence among no-SpA patients): erosions (E) ≥3, fatty lesions (FL) ≥3, E/FL ≥5. Patients were classified according to the ASAS axSpA criteria using the various definitions of MRI-SI-s.
RESULTS:

Of the 582 patients included in this analysis, 418 fulfilled the ASAS axSpA criteria, of which 127 patients were modified New York (mNY) positive and 134 and 75 were MRI-SI-s positive (E/FL≥5) for readers 1 and 2, respectively. Agreement between mNY and MRI-SI-s (E/FL≥5) was moderate (reader 1: κ: 0.39; reader 2: κ: 0.44). Using the E/FL≥5 cut-off instead of mNY classification did not change in 478 (82.1%) and 469 (80.6%) patients for readers 1 and 2, respectively. Twelve (reader 1) or ten (reader 2) patients would not be classified as axSpA if only MRI-SI-s was performed (in the scenario of replacement of mNY), while three (reader 1) or six (reader 2) patients would be additionally classified as axSpA in both scenarios (replacement of mNY and addition of MRI-SI-s). Similar results were seen for the other cut-offs (E≥3, FL≥3).
CONCLUSIONS:

Structural lesions on MRI can be used reliably either as an addition to or as a substitute for radiographs in the ASAS axSpA classification of patients in our cohort of patients with short symptom duration.

Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/
KEYWORDS:

Ankylosing Spondylitis; Low Back Pain; Magnetic Resonance Imaging; Spondyloarthritis

Rate and predisposing factors of sacroiliac radiographic progression after a 2 years follow-up period in recent onset spondyloarthritis

Un nouvel article scientifique intitulé « Rate and predisposing factors of sacroiliac radiographic progression after a 2 years follow-up period in recent onset spondyloarthritis.» a été publié dans le journal Arthritis Rheumatol.
Dougados M, Demattei C, van den Berg R, Hoang VV, Thevenin F, Reijnierse M, Loeuille D, Feydy A, Claudepierre P, van der Heijde D.
Arthritis [...]

Two Phenotypes are Identified by Cluster Analysis in Early Inflammatory Back Pain Suggestive of Spondyloarthritis. Results from the Desir Cohort.

Un nouvel article scientifique intitulé «Two Phenotypes are Identified by Cluster Analysis in Early Inflammatory Back Pain Suggestive of Spondyloarthritis. Results from the Desir Cohort.» a été publié dans le journal Arthritis Rheumatol.
Costantino F, Aegerter P, Dougados M, Breban M, D’Agostino MA
Arthritis Rheumatol. 2016 Feb 11. doi: 10.1002/art.39628.
Abstract
OBJECTIVE:
To examine whether in patients with early inflammatory [...]

Factors associated with a bad functional prognosis in early inflammatory back pain: results from the DESIR cohort.

Un nouvel article scientifique intitulé «Factors associated with a bad functional prognosis in early inflammatory back pain: results from the DESIR cohort.» a été publié dans le journal RMD Open.
Lukas C, Dougados M, Combe B.
RMD Open. 2016 Feb 8;2(1):e000204. doi: 10.1136/rmdopen-2015-000204. eCollection 2016.
Abstract
BACKGROUND:
Spondyloarthritis (SpA) is a heterogeneous disease with hardly predictable potential courses. We [...]

Evaluation of physiotherapy in a prospective cohort of early axial spondyloarthritis. Data from the DESIR cohort.

Un nouvel article scientifique intitulé « Evaluation of physiotherapy in a prospective cohort of early axial spondyloarthritis. Data from the DESIR cohort» a été publié dans le journal Joint Bone Spine.
Escalas C, Dalichampt M, Dougados M, Poiraudeau S.
Joint Bone Spine. 2015 Dec 8. pii: S1297-319X(15)00244-4. doi: 10.1016/j.jbspin.2015.05.008.
Abstract
OBJECTIVE:
To evaluate the effect of physiotherapy on functional limitation in an observational [...]